ozempic

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Retatrutide Summary

Retatrutide is an incretin mimetic and GGG agonist. It binds to glucagon receptors, gastric inhibitory peptide receptors, and glucagon-like peptide-1 receptors. This triple activity has been associated with significant weight loss (24% of body weight at 6 months) in clinical trials. This outcome makes retatrutide the most effective of incretin peptides to date and thus it is under intense investigation as a weight loss agent. There is some hope that retatrutide may also have beneficial cardiovascular effects and might therefore be useful in the treatment of heart disease complicated by diabetes as well as heart disease in general.